Call Us:Office phone:+86-311-86954186
Glomerular filtration membrane plays the function of filtering blood and meanwhile preserving nutrition like protein. Only this process, only a small amount of small molecular protein can pass through this membrane and finally get into urine. Therefore, if urine protein electrophoresis shows most of the protein in urine are macromolecule protein and middle-molecule protein, we need to think about if glomerular filtration membrane is damaged for some reasons.
As we have mentioned above, only a small amount of small molecular protein can pass through filtration membrane. Most of these proteins are finally reabsorbed by renal tubule. Therefore, appearance of excess small molecular protein in urine always indicates disorder of renal tubule.
Mixed proteinuria is formed when both glomerulus and renal tubule are damaged. Under such a condition, through urine protein electrophoresis, we can find there are excess macromolecular protein and micromolecular protein in urine. Additional, mixed proteinuria appears easily when kidney problem develops to advanced stage.