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Diagnosis of Hematuria

Diagnosis of HematuriaHematuria refers to the presence of excess red blood cells in urine. It is an abnormal medical condition and also a common symptom of kidney disease. Hematuria is clinically divided into two types: Microscopic Hematuria and Gross Hematuria. Analysis about hematuria helps us know well about the exact location of kidney damages, which lays a foundation for the following treatment. Therefore, it is necessary for every kidney disease patient to have this test.

So far phase-contrast urine microscopy and automated peripheral blood cell counter are the most commonly used two methods that can help us know well about if the excess red blood cells leak into urine due to damaged glomerular filtration membrane:
 

1. Generally speaking, if red blood cells leak into urine due to damaged glomerular filtration membrane, red blood cells found in urine are usually various in both shape and size and in such a case, glomerular hematuria is diagnosed.
 

2. While passing through glomerular filtration membrane, erythrocytes lose hemoglobin pigment easily, which makes their color light. Therefore, glomerular erythrocytes look paler than nonglomerular erythrocytes.
 

3. Besides, in some cases, we may find about a half of red blood cells found in urine are mishappen and another half are normal. Under such a condition, mixed hematuria should be put into consideration.

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